Streptococcus invasive locus (sil) in Group A Streptococcus causing non-invasive infections in Chennai, South India
نویسندگان
چکیده
Introduction Group A Streptococcus (GAS) causes diseases ranging from superficial skin & throat infections to severe lifethreatening diseases. Streptococcus invasive locus (sil) is a virulence gene responsible for pathogenesis of GAS. This study intends to detect the presence of sil gene among the non-invasive GAS and its association with toxin genes, erythromycin resistance genes, and emm types.
منابع مشابه
Molecular epidemiology of sil locus in clinical Streptococcus pyogenes strains.
Streptococcus pyogenes (group A Streptococcus [GAS]) causes a wide variety of diseases, ranging from mild noninvasive to severe invasive infections. Mutations in regulatory components have been implicated in the switch from colonization to invasive phenotypes. The inactivation of the sil locus, composed of six genes encoding a quorum-sensing complex, gives rise to a highly invasive strain. Howe...
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